Incidence of Metachronous Testicular Cancer in Patients With Extragonadal Germ Cell Tumors
نویسندگان
چکیده
منابع مشابه
Should extragonadal germ cell tumors be included in studies of families with testicular germ cell tumors?
BACKGROUND Family history is among the few established risk factors for testicular germ cell tumor (TGCT). Approximately 1.4% of newly diagnosed TGCT patients report a positive family history of TGCT. Sons and siblings of TGCT patients have four- to six fold and eight- to tenfold increase in TGCT risk, respectively. In twins of men with TGCT the relative risk of testicular cancer is 37.5 (12.3-...
متن کاملExtragonadal germ cell tumors.
Germ cell cancer is the most common malignancy in men aged 15–35 years; 5% of the malignant germ cell tumors are of extragonadal origin [1]. An extragonadal germ cell tumor (EGGCT) is by definition a germ cell neoplasm displaying one of the histologies associated with gonadal origin, but located outside of the gonads. This specific clinical entity was first described in the 19th century [2, 3]....
متن کاملgenetics of testicular germ cell tumors
testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...
متن کاملBilateral testicular germ cell tumors.
Testicular cancer represents 1% to 1.5% of neoplasias in males and 5% of urologic tumors in general. The incidence of bilateral testicular tumors is 1-5%. Approximately one third of the cases are diagnosed as synchronous, while the other two thirds are diagnosed as metachronous tumors. Additionally, 5% of all patients diagnosed with testicular cancer may have contralateral intratubular germ cel...
متن کاملProtocol for the examination of specimens from pediatric and adult patients with extragonadal germ cell tumors.
Authors Amy Heerema-McKenney, MD* Department of Pathology, Stanford University, Palo Alto, California Jay Bowen, MS Center for Childhood Cancer, Columbus Children’s Research Institute, Columbus, Ohio D. Ashley Hill, MD Department of Pathology, Children’s National Medical Center, Washington, DC Stephen J. Qualman, MD** Center for Childhood Cancer, Columbus Children’s Research Institute, Columbus...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2001
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/93.22.1733